What is the appropriate treatment for gonorrhea?

The appropriate treatment for gonorrhea is intramuscular ceftriaxone combined with oral azithromycin. This dual therapy is recommended to effectively eradicate the Neisseria gonorrhoeae bacteria that cause the infection and to address the rising concern of antibiotic resistance. Ceftriaxone acts as a broad-spectrum cephalosporin antibiotic, which is very effective against gonococcal infections. Adding azithromycin, a macrolide antibiotic, helps to ensure that potential co-infections, such as chlamydia, are treated as well.

This combination therapy is endorsed by public health guidelines, as it enhances efficacy and helps minimize the likelihood of treatment failure, especially in light of evolving resistance patterns among gonococcal strains. The other treatment options do not address gonorrhea adequately, either because they target other pathogens or do not have the necessary spectrum of activity.